POSTER: Evaluating Novel Whole Blood Preservation Methods as Alternatives to PBMC for Immunophenotyping in Multicenter Clinical Trials
This study assessed three whole blood preservation methods—CryoStor CS10, Cytodelics, and Smart Tube—as PBMC alternatives for flow cytometry. Using a 26-color panel, CryoStor CS10 showed the most consistent results. Cytodelics and Smart Tube had more variability, likely due to fixatives. CryoStor is a strong alternative, though donor variability and antibody re-titration should be considered.