Resources

BLOG: dPCR, qPCR, and RT-qPCR - Navigating Advantages and Challenges in Preclinical and Clinical Development

Explore the strengths and limitations of dPCR, qPCR, and RT-qPCR in preclinical and clinical development. Learn how these PCR technologies differ, their key applications, and best practices for assay design and validation to ensure accurate, reliable results.

POSTER: Comparative Performance of Bio-Rad QX200 and VibroJet DQ24 ddPCR Platforms for BRAF V600E Detection

This study compares the Bio-Rad QX200 and VibroJet DQ24 ddPCR systems for BRAF V600E detection, showing strong agreement. The DQ24 offers greater sensitivity, automation, and throughput, while the QX200 provides slightly higher precision.

POSTER: Comparison of Novel Whole Blood Preservation Methods as Alternatives to Cryopreserved PBMC for Immunophenotyping in Multicenter Clinical Trials

CryoStor CS10 outperformed other whole blood preservation methods, offering a reliable alternative to PBMC for immunophenotyping in multicenter trials.

POSTER: Comparative Analysis of Replication-Competent Vector Quantification: Whole Blood vs. PBMCs in Gene Therapy Monitoring

This study found that whole blood offers higher sensitivity and easier handling than PBMCs for RCL quantification, providing a faster and practical alternative for gene therapy monitoring with comparable accuracy.

ARTICLE: Technical Considerations of Pharmacokinetic Assays for LNP‑mRNA Drug Products by RT‑qPCR

Guidance on developing and validating RT-qPCR assays to support pharmacokinetic analysis of LNP-mRNA drug products, ensuring reliable and consistent bioanalytical results.

WHITE PAPER: Analytical Validation of Whole Exome Sequencing (WES) Using Saliva, Buccal Swab, and Whole Blood Matrices

Eurofins Viracor BioPharma validated a Whole Exome Sequencing (WES) assay across saliva, buccal swab, and whole blood samples, demonstrating high accuracy, precision, and stability. The results confirm the assay’s reliability for genomic profiling using multiple sample types.

ON-DEMAND WEBINAR: RNA Whole Transcriptome Sequencing from Challenging Matrices - Insights from Tissue

September 17, 2025

Learn practical strategies to improve RNA extraction and sequencing from challenging tissue samples in this on-demand eChalk Talk with Lori Breece and Dr. Karina Eterovic.

BLOG: Core vs. Full Process Validation - Choosing the Right Path for PCR Assay Confidence

In PCR assay development, choosing the right validation approach is critical for data integrity and regulatory success. This blog explains the differences between core and full process validation—and when to use each.

ON-DEMAND WEBINAR: Successful Nucleic Acid Extraction - The Linchpin for PCR Bioanalysis

July 24, 2025

Discover how evolving regulatory expectations impact analytical testing for cell and gene therapies. Dr. Mark Wissel shares practical strategies for effective nucleic acid extraction to support clinical success.

BLOG: Navigating the Maze - How Biopharma Trials Stay Compliant from Lab Bench to Regulatory Benchmarks

Whether you're pipetting in a preclinical lab, managing samples in a trial, or compiling data for a submission, compliance is the invisible thread stitching every step together. We unpack how biopharma teams align with regulatory expectations through GLP, GCP, GCLP, and the ever-growing library of regulatory guidelines.

Scientific Expertise